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FBXW12 Antibody, FITC Conjugated

FBXW12 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, FBXW12 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFBXW12
SpecificityThis is a highly specific antibody against FBXW12
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FBXW12/FBXO35
Gene ID number285231
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein)-type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, FBXO35 (F-box only protein 35), FBXO35 can directly interact with Skp1 p19 and CUL-1, FBXO35 is ubiquitously expressed at low levels in most human tissues, I&, They are members of a larger family of proteins that are involved in the regulation of a wide variety of cellular mechanisms, They function by targeting proteins, Via its F-box domain, also designated F-box and WD-40 domain-containing protein 12 (FBXW12 or FBXO12), and â, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, including the cell cycle, is a 464 amino acid protein that contains one C-terminal F-box domain, signaling cascades and developmental processes, such as cyclins, the immune response, #730, &circ, «, -catenin, B-&, Belonging to the F-box family of proteins, aring
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms Fbw12
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFBXW12 Conjugated
Short name FITC Conjugated, FBXW12 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, FBXW12 (Antibody to)
Alternative techniqueantibodies
Identity 20729
Gene FBXW12
Long gene name F-box and WD repeat domain containing 12
Synonyms gene FBXO35
Synonyms gene name F-box only protein 35 F-box and WD-40 domain protein 12
Locus 3p21, 31
Discovery year 2003-04-04
GenBank acession AK097594 AY247969
Entrez gene record 285231
Pubmed identfication 15040455
RefSeq identity NM_207102
Classification F-box and WD repeat domain containing WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000133530

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