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Fbxw7 Antibody

Fbxw7 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFbxw7 Primary Polyclonal Antibody
Also known asFbxw7 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFbxw7
SpecificityThis is a highly specific antibody against Fbxw7
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range519-549/707
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Fbxw7/hCDC4
Gene ID number55294
Swiss ProtQ969H0
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a negative regulator of JNK signaling by binding to phosphorylated JUN and promoting its ubiquitination and subsequent degradation (PubMed:14739463), Identified substrates include cyclin-E (CCNE1 or CCNE2), JUN, MYC, NOTCH1 released notch intracellular domain (NICD), PubMed:11585921, PubMed:12354302, PubMed:14739463, PubMed:15103331, PubMed:17558397, PubMed:17873522, PubMed:22608923), Recognizes and binds phosphorylated sites/phosphodegrons within target proteins and thereafter bring them to the SCF complex for ubiquitination (PubMed:17434132), and probably PSEN1 (PubMed:11565034, Substrate recognition component of an SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Archipelago homolog, CDC4, F-box and WD-40 domain-containing protein 7, F-box protein FBX30, F-box/WD repeat-containing protein 7, FBW6, FBW7, FBX30, FBXO30, FBXW6, FBXW7, SEL-10, SEL10, hAgo, hCdc4, AGO
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFbxw7
Short nameFbxw7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFbxw7 (Antibody to)
Alternative techniqueantibodies
Identity 52397
Gene FBXW7-AS1
Long gene name FBXW7 antisense RNA 1
Synonyms DEAR DEspR
Synonyms name dual-endothelin1/VEGFsp receptor dual endothelin-1(VEGFsp)/angiotensin II receptor
Locus 4q31, 3
Discovery year 2016-10-13
Entrez gene record 102191832

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