Name : FBXW8 Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3448784706
| Long name | ALEXA FLUOR 647 Conjugated, FBXW8 Polyclonal Antibody |
| Also known as | Anti-FBXW8 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FBXW8 |
| Specificity | This is a highly specific antibody against FBXW8 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FBXW8/FBXO29 |
| Gene ID Number | 26259 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, F-box proteins are members of a large family that regulates cell cycle, FBXO29 also contains five WD repeats, FBXO29 exists as two isoforms as a result of alternative splicing events, FBXO29 is thought to recognize and bind to select phosphorylated proteins, Functioning as a component of the SCF complex, IkB-&, also designated F-box/WD repeat-containing protein 8 (FBXW8), and â, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, immune response, is a 598 amino acid protein that contains one 40 amino acid F-box region, making it a member of the F-box family, signaling cascades and developmental programs by targeting proteins, such as cyclins, thereby promoting their ubiquitination and subsequent degradation, &circ, «, -catenin, FBXO29, aring |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | FBX29 FBW6 FBW8 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the FBXW8 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | FBXW8 |
| Short name | FBXW8 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, FBXW8 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13597 |
| Gene | FBXW8 |
| Long gene name | F-box and WD repeat domain containing 8 |
| Synonyms gene | FBXO29 |
| Synonyms gene name | F-box only protein 29 F-box and WD-40 domain protein 8 |
| Locus | 12q24, 22 |
| Discovery year | 2000-09-27 |
| GenBank acession | AF176707 |
| Entrez gene record | 26259 |
| Pubmed identfication | 10531035 10531037 |
| RefSeq identity | NM_012174 |
| Classification | F-box and WD repeat domain containing WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000169329 |