Name : FBXW8 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9383776964
| Long name | Biotin Conjugated, FBXW8 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FBXW8 |
| Specificity | This is a highly specific antibody against FBXW8 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human FBXW8/FBXO29 |
| Gene ID number | 26259 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, F-box proteins are members of a large family that regulates cell cycle, FBXO29 also contains five WD repeats, FBXO29 exists as two isoforms as a result of alternative splicing events, FBXO29 is thought to recognize and bind to select phosphorylated proteins, Functioning as a component of the SCF complex, IkB-&, also designated F-box/WD repeat-containing protein 8 (FBXW8), and â, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, immune response, is a 598 amino acid protein that contains one 40 amino acid F-box region, making it a member of the F-box family, signaling cascades and developmental programs by targeting proteins, such as cyclins, thereby promoting their ubiquitination and subsequent degradation, &circ, «, -catenin, FBXO29, aring |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | FBX29 FBW6 FBW8 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FBXW8 Conjugated |
| Short name | Conjugated, FBXW8 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, FBXW8 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13597 |
| Gene | FBXW8 |
| Long gene name | F-box and WD repeat domain containing 8 |
| Synonyms gene | FBXO29 |
| Synonyms gene name | F-box only protein 29 F-box and WD-40 domain protein 8 |
| Locus | 12q24, 22 |
| Discovery year | 2000-09-27 |
| GenBank acession | AF176707 |
| Entrez gene record | 26259 |
| Pubmed identfication | 10531035 10531037 |
| RefSeq identity | NM_012174 |
| Classification | F-box and WD repeat domain containing WD repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000169329 |