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FBXW8 Antibody, FITC Conjugated

FBXW8 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, FBXW8 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFBXW8
SpecificityThis is a highly specific antibody against FBXW8
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FBXW8/FBXO29
Gene ID number26259
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, F-box proteins are members of a large family that regulates cell cycle, FBXO29 also contains five WD repeats, FBXO29 exists as two isoforms as a result of alternative splicing events, FBXO29 is thought to recognize and bind to select phosphorylated proteins, Functioning as a component of the SCF complex, IkB-&, also designated F-box/WD repeat-containing protein 8 (FBXW8), and â, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, immune response, is a 598 amino acid protein that contains one 40 amino acid F-box region, making it a member of the F-box family, signaling cascades and developmental programs by targeting proteins, such as cyclins, thereby promoting their ubiquitination and subsequent degradation, &circ, «, -catenin, FBXO29, aring
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FBX29 FBW6 FBW8
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFBXW8 Conjugated
Short name FITC Conjugated, FBXW8 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, FBXW8 (Antibody to)
Alternative techniqueantibodies
Identity 13597
Gene FBXW8
Long gene name F-box and WD repeat domain containing 8
Synonyms gene FBXO29
Synonyms gene name F-box only protein 29 F-box and WD-40 domain protein 8
Locus 12q24, 22
Discovery year 2000-09-27
GenBank acession AF176707
Entrez gene record 26259
Pubmed identfication 10531035 10531037
RefSeq identity NM_012174
Classification F-box and WD repeat domain containing WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000169329

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