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FCGRT Antibody

FCGRT Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenFCGRT
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the FCGRT antibody should be determined by the researcher
Intented useThis FCGRT antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P55899
PurityAntigen affinity
Description In addition, The FCGRT gene is closely situated to the DMPK gene, The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta, This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G, This protein also binds immunoglobulin G to protect the antibody from degradation, it is postulated that long-range cis inactivation of the FCGRT gene is responsible for hypercatabolism of IgG in myotonic dystrophy, which is mutant in DM, IgG receptor FcRn large subunit p51 is a protein that in humans is encoded by the FCGRT gene
ImmunogenAmino acids 56-291 of human FCGRT were used as the immunogen for the FCGRT antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the FCGRT antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
LocalizationCytoplasmic
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetFCGRT
Short nameFCGRT Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name alpha (Antibody to), receptor, transporter, fragment c fragment on Immunoglobulin G
Alternative techniqueantibodies
Alternative to gene target FCGRT and IDBG-63001 and ENSG00000104870 and 2217, FCGRT and IDBG-640575 and ENSBTAG00000013926 and 338062, Fcgrt and IDBG-181534 and ENSMUSG00000003420 and 14132, Plasma membranes, alpha, alpha-chain and FCRN, beta-2-microglobulin binding, receptor, this GO :0002416 and IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor and biological process this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0006955 and immune response and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0019864 and IgG binding and molecular function this GO :0019882 and antigen processing and presentation and biological process this GO :0030881 and beta-2-microglobulin binding and molecular function this GO :0038094 and Fc-gamma receptor signaling pathway and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0019864: IgG binding and also this GO :0030881: beta-2-microglobulin binding, this GO :0019864: IgG binding, this GO :0030881: beta-2-microglobulin binding, transporter, Fc fragment of IgG
Identity 3621
Gene FCGRT
Long gene name Fc fragment of IgG receptor and transporter
Synonyms gene name Fc fragment of IgG, alpha , receptor, transporter
Synonyms FCRN alpha-chain
Synonyms name heavy chain of the major histocompatibility complex class I-like Fc receptor transmembrane alpha chain of the neonatal receptor
Locus 19q13, 33
Discovery year 1995-08-23
GenBank acession U12255
Entrez gene record 2217
Pubmed identfication 7964511 8646894
Classification C1-set domain containing
Havana BLAST/BLAT OTTHUMG00000183155

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