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FE65 Antibody, Cy7 Conjugated

FE65 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, FE65 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFE65
SpecificityThis is a highly specific antibody against FE65
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range225-265/710
Subcellular location Cell membrane, Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human Fe65 protein
Gene ID number322
Swiss ProtO00213
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain, Associates with chromatin in a region surrounding the CASP4 transcriptional start site(s), Function in association with TSHZ3, Its ability to specifically bind modified histones and chromatin modifying enzymes such as KAT5/TIP60, May act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), Plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis, Required for histone H4 acetylation at double-strand breaks (DSBs), SET and HDAC factors as a transcriptional repressor, probably explains its trancription activation activity, recruiting other pro-apoptosis factors such as MAPK8/JNK1, that inhibits the expression of CASP4, Transcription coregulator that can have both coactivator and corepressor functions
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms Fe65
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetFE65 Conjugated
Short name Conjugated, FE65 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, FE65 (Antibody to)
Alternative techniqueantibodies
Identity 581
Gene APBB1
Long gene name amyloid beta precursor protein binding family B member 1
Synonyms gene RIR
Synonyms gene name amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
Locus 11p15, 4
Discovery year 1997-03-27
GenBank acession L77864
Entrez gene record 322
Pubmed identfication 8955346 8894693
RefSeq identity NM_001164
Havana BLAST/BLAT OTTHUMG00000165454

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