Name : FECH Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8838120468
| Long name | ALEXA FLUOR 488 Conjugated, FECH Polyclonal Antibody |
| Also known as | Anti-FECH PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FECH |
| Specificity | This is a highly specific antibody against FECH |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human EPB41 |
| Gene ID Number | 2235 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Defects in ferrochelatase are associated with protoporphyria, Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway), They are broadly classified as hepatic porphyrias or erythropoietic porphyrias, They manifest with either skin problems, Two transcript variants encoding different isoforms have been found for this gene, and is localised in the mitochondrion, based on the site of the overproduction and mainly accumulation of the porphyrins (or their chemical precursors), or neurological complications, or occasionally both, Ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the FECH Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | FECH |
| Short name | FECH Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, FECH (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3647 |
| Gene | FECH |
| Long gene name | ferrochelatase |
| Synonyms gene name | ferrochelatase (protoporphyria) |
| Synonyms name | protoporphyria |
| Locus | 18q21, 31 |
| Discovery year | 1990-05-14 |
| GenBank acession | D00726 |
| Entrez gene record | 2235 |
| Pubmed identfication | 1838349 |
| Havana BLAST/BLAT | OTTHUMG00000132740 |
| Locus Specific Databases | LRG_1080 |