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FEN1 Antibody

FEN1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFEN1 Primary Polyclonal Antibody
Also known asFEN1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFEN1
SpecificityThis is a highly specific antibody against FEN1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FEN1
Gene ID number2237
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions, Also involved in replication and repair of rDNA and in repairing mitochondrial DNA, Also involved in the long patch base excision repair (LP-BER) pathway, Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, During DNA replication, It enters the flap from the 5'-end and then tracks to cleave the flap base, and exhibits RNase H activity, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment, leaving a nick for ligation, Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FEN-1, FEN1, FEN1_HUMAN, Flap endonuclease 1, Flap structure specic endonuclease 1, Flap structure-specic endonuclease 1, MF1, Rad2, hFEN-1, hFEN1, DNase IV, Maturation factor 1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFEN1
Short nameFEN1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFEN1 (Antibody to)
Alternative techniqueantibodies
Identity 3650
Gene FEN1
Long gene name flap structure-specific endonuclease 1
Synonyms gene RAD2
Synonyms FEN-1 MF1
Synonyms name maturation factor-1 DNase IV
Locus 11q12, 2
Discovery year 1995-02-03
GenBank acession L37374
Entrez gene record 2237
Pubmed identfication 7774922
RefSeq identity NM_004111
Havana BLAST/BLAT OTTHUMG00000168162

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