Name : FEN1 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6913669956
| Long name | ALEXA FLUOR 594 Conjugated, FEN1 Polyclonal Antibody |
| Also known as | Anti-FEN1 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FEN1 |
| Specificity | This is a highly specific antibody against FEN1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FEN1 |
| Gene ID Number | 2237 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions, Also involved in replication and repair of rDNA and in repairing mitochondrial DNA, Also involved in the long patch base excision repair (LP-BER) pathway, Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, During DNA replication, It enters the flap from the 5'-end and then tracks to cleave the flap base, and exhibits RNase H activity, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment, leaving a nick for ligation, Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | FEN-1 MF1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | FEN1 |
| Short name | FEN1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, FEN1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3650 |
| Gene | FEN1 |
| Long gene name | flap structure-specific endonuclease 1 |
| Synonyms gene | RAD2 |
| Synonyms name | maturation factor-1 DNase IV |
| Locus | 11q12, 2 |
| Discovery year | 1995-02-03 |
| GenBank acession | L37374 |
| Entrez gene record | 2237 |
| Pubmed identfication | 7774922 |
| RefSeq identity | NM_004111 |
| Havana BLAST/BLAT | OTTHUMG00000168162 |