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FEN1 Antibody, ALEXA FLUOR 594

FEN1 Antibody, ALEXA FLUOR 594 size: 100ul 332

Price 332
Size 100ul
Long name ALEXA FLUOR 594 Conjugated, FEN1 Polyclonal Antibody
Also known asAnti-FEN1 PAb ALEXA FLUOR 594
CategoryConjugated Primary Antibodies
Conjugated with 594, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFEN1
SpecificityThis is a highly specific antibody against FEN1
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FEN1
Gene ID Number2237
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions, Also involved in replication and repair of rDNA and in repairing mitochondrial DNA, Also involved in the long patch base excision repair (LP-BER) pathway, Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, During DNA replication, It enters the flap from the 5'-end and then tracks to cleave the flap base, and exhibits RNase H activity, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment, leaving a nick for ligation, Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission590nm/617nm
Synonyms FEN-1 MF1
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation 594, ALEXA FLUOR®, Alexa Fluor
ConjugatedAlexa conjugate 1
Gene targetFEN1
Short nameFEN1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 594
Alternative name ALEXA FLUOR 594, FEN1 (Antibody to)
Alternative techniqueantibodies
Identity 3650
Gene FEN1
Long gene name flap structure-specific endonuclease 1
Synonyms gene RAD2
Synonyms name maturation factor-1 DNase IV
Locus 11q12, 2
Discovery year 1995-02-03
GenBank acession L37374
Entrez gene record 2237
Pubmed identfication 7774922
RefSeq identity NM_004111
Havana BLAST/BLAT OTTHUMG00000168162

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