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FEN1 Antibody, Biotin Conjugated

FEN1 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, FEN1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFEN1
SpecificityThis is a highly specific antibody against FEN1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FEN1
Gene ID number2237
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions, Also involved in replication and repair of rDNA and in repairing mitochondrial DNA, Also involved in the long patch base excision repair (LP-BER) pathway, Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, During DNA replication, It enters the flap from the 5'-end and then tracks to cleave the flap base, and exhibits RNase H activity, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment, leaving a nick for ligation, Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FEN-1 MF1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFEN1 Conjugated
Short name Conjugated, FEN1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, FEN1 (Antibody to)
Alternative techniqueantibodies
Identity 3650
Gene FEN1
Long gene name flap structure-specific endonuclease 1
Synonyms gene RAD2
Synonyms name maturation factor-1 DNase IV
Locus 11q12, 2
Discovery year 1995-02-03
GenBank acession L37374
Entrez gene record 2237
Pubmed identfication 7774922
RefSeq identity NM_004111
Havana BLAST/BLAT OTTHUMG00000168162

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