Name : Fer (1487CT794.8.50) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN8526851948
| Long name | 50) Monoclonal Antibody, 8, Fer (1487CT794 |
| Also known as | 50) Monoclonal Antibody, 8, Fer (1487CT794 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | Fer |
| Specificity | This is a highly specific antibody against Fer |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1487CT794, 8, 50 |
| Source | This Fer antibody is generated from a mouse immunized with a recombinant protein |
| Gene ID number | 14158 |
| Swiss Prot | P70451 |
| Tested Applications | FCM, IF, WB |
| Recommended dilutions | FC(1:25), IF(1:25) , WB(1:4000) |
| Cross reactivity | Mouse |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | According to PubMed:11134346, Acts downstream of EGFR, Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation, Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells, CTNND1, Can phosphorylate STAT3 according to PubMed:10878010 and PubMed:19159681, GAB1, Isoform 3 lacks kinase activity, KIT, May phosphorylate JUP and PTPN1, May play a role in the regulation of the mitotic cell cycle, PDGFRA and PDGFRB, PECAM1 and PTPN11, PTK2/FAK1, Phosphorylates CTTN, Phosphorylates TMF1, Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide (LPS), Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase, Plays a role in the regulation of mast cell degranulation, but clearly plays a redundant role in STAT3 phosphorylation, cell adhesion, cell migration and chemotaxis, cells where wild type FER has been replaced by a kinase-dead mutant show no reduction in STAT3 phosphorylation, lamellipodia formation, microtubule assembly, Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | AV082135, C330004K01Rik, Fert, Fert2, Proto-oncogene c-Fer, Tyrosine-protein kinase Fer, p94-Fer, Fer |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 50) Monoclonal, 8, Fer (1487CT794 |
| Short name | 50) Monoclonal Antibody, 8, Fer (1487CT794 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 50) monoclonal (Antibody to), 8, fer (fps/fes related) tyrosine kinase (1487CT794 |
| Alternative technique | antibodies |