Name : FES (1467CT528.22.17) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :211
SKU : GEN4639903105
| Long name | 17) Monoclonal Antibody, 22, FES (1467CT528 |
| Also known as | 17) Monoclonal Antibody, 22, FES (1467CT528 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | FES |
| Specificity | This is a highly specific antibody against FES |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 1467CT528, 17, 22 |
| Source | This FES antibody is generated from a mouse immunized with a recombinant protein |
| Gene ID number | 2242 |
| Swiss Prot | P07332 |
| Tested Applications | IHC-P, WB |
| Recommended dilutions | WB(1:1000-2000), IHC-P(1:25) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts down-stream of the activated FCER1 receptor and the mast/stem cell growth factor receptor KIT, PECAM1, Phosphorylates BCR and down-regulates BCR kinase activity, Phosphorylates HCLS1/HS1, Plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells, Plays a role in cell scattering and cell migration in response to HGF-induced activation of EZR, Plays a role in the regulation of cell differentiation and promotes neurite outgrowth in response to NGF signaling, Plays a role in the regulation of mast cell degranulation, STAT3 and TRIM28, cell attachment and cell spreading, microtubule assembly, Tyrosine-protein kinase that acts downstream of cell surface receptors and plays a role in the regulation of the actin cytoskeleton |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | FES, Feline sarcoma/Fujinami avian sarcoma oncogene homolog, Proto-oncogene c-Fes, Proto-oncogene c-Fps, Tyrosine-protein kinase Fes/Fps, p93c-fes, FPS |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 17) Monoclonal, 22, FES (1467CT528 |
| Short name | 17) Monoclonal Antibody, 22, FES (1467CT528 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 17) monoclonal (Antibody to), 22, FES (1467CT528 |
| Alternative technique | antibodies |
| Identity | 3657 |
| Gene | FES |
| Long gene name | FES proto-oncogene, tyrosine kinase |
| Synonyms gene name | feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami avian sarcoma (PRCII) viral (v-fps) oncogene homolog feline sarcoma oncogene |
| Synonyms | FPS |
| Synonyms name | Oncogene FES, feline sarcoma virus c-fes/fps protein |
| Locus | 15q26, 1 |
| Discovery year | 2001-06-22 |
| GenBank acession | X52192 |
| Entrez gene record | 2242 |
| Pubmed identfication | 1870997 |
| RefSeq identity | NM_002005 |
| Classification | SH2 domain containing F-BAR domain containing |
| Havana BLAST/BLAT | OTTHUMG00000044456 |