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FEZ1 Antibody, Biotin Conjugated

FEZ1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, FEZ1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFEZ1
SpecificityThis is a highly specific antibody against FEZ1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FEZ1
Gene ID number9638
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background During cell-cycle progression, FEZ1 acts as a negative regulator of cell growth, FEZ1 is expressed in normal breast and prostate, FEZ1 localizes to microtubule components and is hyperphosphorylated by cAMP-dependent kinase, The 8p22-p21 region contains the FEZ1 gene, The FEZ1 protein (also known as leucine zipper putative tumor suppressor or LZTS1) contains a DNA-binding leucine zipper motif, The absence of FEZ1 expression is characteristic of breast and prostate cancer cell lines as well as primary breast and pro-state tumors, This absence of FEZ1 may be due to several factors, but alterations in FEZ1 expression result in abnormal cell growth, including mutations in the FEZ1 gene or hypermethylation of the CpG island flanking the FEZ1 promoter region, prostate and breast, which is altered in tumors of the esophagus, Frequent loss of heterozygosity (LOH) at human chromosome 8p22-p21 is associated with various tumors including prostate and breast cancer
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms UNC-76
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFEZ1 Conjugated
Short name Conjugated, FEZ1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, fasciculation and elongation protein zeta 1 (zygin I) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target FEZ1 and IDBG-642679 and ENSBTAG00000009124 and 511751, FEZ1 and IDBG-75464 and ENSG00000149557 and 9638, Fez1 and IDBG-149600 and ENSMUSG00000032118 and 235180, Plasma membranes, protein N-terminus binding, this GO :0005080 and protein kinase C binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005813 and centrosome and cellular component this GO :0005874 and microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006810 and transport and biological process this GO :0007155 and cell adhesion and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process this GO :0010976 and positive regulation of neuron projection development and biological process this GO :0015630 and microtubule cytoskeleton and cellular component this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0042995 and cell projection and cellular component this GO :0043015 and gamma-tubulin binding and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0047485 and protein N-terminus binding and molecular function this GO :0051654 and establishment of mitochondrion localization and biological process this GO :0071363 and cellular response to growth factor stimulus and biological process, this GO :0005080: protein kinase C binding, this GO :0005080: protein kinase C binding and also this GO :0005515: protein binding and also this GO :0043015: gamma-tubulin binding and also this GO :0047485: protein N-terminus binding, this GO :0005515: protein binding, this GO :0043015: gamma-tubulin binding, this GO :0047485: protein N-terminus binding, fasciculation and elongation protein zeta 1 (zygin I)
Identity 3659
Gene FEZ1
Long gene name fasciculation and elongation protein zeta 1
Synonyms name zygin I
Locus 11q24, 2
Discovery year 1999-12-14
GenBank acession U60060
Entrez gene record 9638
Pubmed identfication 9096408 15843383
RefSeq identity NM_005103
Havana BLAST/BLAT OTTHUMG00000165886

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