Name : FEZ2/Zygin2 Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3361009882
| Long name | ALEXA FLUOR 555 Conjugated, FEZ2/Zygin2 Polyclonal Antibody |
| Also known as | Anti-FEZ2/Zygin2 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FEZ2/Zygin2 |
| Specificity | This is a highly specific antibody against FEZ2/Zygin2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FEZ2/Zygin2 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | As component of the network of molecules that regulate cellular morphology and axon guidance machinery, Expressed mainly in brain, Mutations in the gene encoding zygin 1 may be linked to the pathogenesis of schizophrenia, PKC zeta also enhances zygin 1 interaction with UFD2 and polyubiquitination, Zygin 1 exists as two alternatively spliced isoforms that are designated isoform long and isoform short, Zygin 2 is found as a difulfide-linked homodimer but may for heterodimers with FEZ1, elegans UNC-76 mutants, the plasma membrane to the cytoplasm by activation of PKC zeta, which suggest a functional role in axonal outgrowth, zygin 1 is a mammalian ortholog of Caenorhabditis elegans UNC-76 and is able to restore partial locomotion and axonal fasciculation to C, zygin 1 may also be involved in microtubule associated transport and transcriptional regulation, Zygin 2 is a 353 amino acid cytoplasmic protein that belongs to the zygin family |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | FEZ2/Zygin2 |
| Short name | FEZ2/Zygin2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, fasciculation and elongation protein zeta 2 (zygin II)/Zygin2 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | FEZ2 and IDBG-44299 and ENSG00000171055 and 9637, FEZ2 and IDBG-632353 and ENSBTAG00000009021 and 100299092, Fez2 and IDBG-198635 and ENSMUSG00000056121 and 225020, HUM3CL, multiple, protein binding, this GO :0005515 and protein binding and molecular function this GO :0007165 and signal transduction and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding, fasciculation and elongation protein zeta 2 (zygin II) |
| Identity | 3660 |
| Gene | FEZ2 |
| Long gene name | fasciculation and elongation protein zeta 2 |
| Synonyms name | zygin II |
| Locus | 2p22, 2 |
| Discovery year | 1999-12-14 |
| GenBank acession | U60061 |
| Entrez gene record | 9637 |
| Pubmed identfication | 9096408 |
| Havana BLAST/BLAT | OTTHUMG00000152148 |