Name : FGG (546CT11.4.3) Monoclonal Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :328
SKU : GEN6602539144
| Long name | 3) Monoclonal Antibody, 4, FGG (546CT11 |
| Also known as | 3) Monoclonal Antibody, 4, FGG (546CT11 |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | FGG |
| Specificity | This is a highly specific antibody against FGG |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Monoclonal |
| Clone number | 3, 4, 546CT11 |
| Source | This FGG antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 417-445 amino acids from human FGG |
| Gene ID number | 2266 |
| Swiss Prot | P02679 |
| Tested Applications | WB |
| Recommended dilutions | WB(1:200~1600) |
| Cross reactivity | Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway, Fibrin deposition is also associated with infection, Has a major function in hemostasis as one of the primary components of blood clots, However, In addition, Maternal fibrinogen is essential for successful pregnancy, May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways, Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization, polymerizes to form an insoluble fibrin matrix, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo, where it protects against IFNG-mediated hemorrhage, Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB) |
| Purification method | 09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0 |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | FGG, PRO2061, Fibrinogen gamma chain |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Gene target | 3) Monoclonal, 4, FGG (546CT11 |
| Short name | 3) Monoclonal Antibody, 4, FGG (546CT11 |
| Technique | Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 3) monoclonal (Antibody to), 4, fibrinogen gamma chain (546CT11 |
| Alternative technique | antibodies |
| Alternative to gene target | Extracellular, FGG and IDBG-42165 and ENSG00000171557 and 2266, FGG and IDBG-628944 and ENSBTAG00000006745 and 280792, Fgg and IDBG-154510 and ENSMUSG00000033860 and 99571, bridging, bridging and also this GO :0046872: metal ion binding and also this GO :0050839: cell adhesion molecule binding, bridging and molecular function this GO :0031091 and platelet alpha granule and cellular component this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0034116 and positive regulation of heterotypic cell-cell adhesion and biological process this GO :0043623 and cellular protein complex assembly and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0045921 and positive regulation of exocytosis and biological process this GO :0046872 and metal ion binding and molecular function this GO :0050714 and positive regulation of protein secretion and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0051258 and protein polymerization and biological process this GO :0051592 and response to calcium ion and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070527 and platelet aggregation and biological process this GO :0072562 and blood microparticle and cellular component this GO :0090277 and positive regulation of peptide hormone secretion and biological process this GO :1900026 and positive regulation of substrate adhesion-dependent cell spreading and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process, protein binding, this GO :0002576 and platelet degranulation and biological process this GO :0005102 and receptor binding and molecular function this GO :0005198 and structural molecule activity and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005577 and fibrinogen complex and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0007160 and cell-matrix adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0030168 and platelet activation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030674 and protein binding, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005198: structural molecule activity and also this GO :0030674: protein binding, this GO :0005198: structural molecule activity, this GO :0030674: protein binding, this GO :0046872: metal ion binding, this GO :0050839: cell adhesion molecule binding, fibrinogen gamma chain |
| Identity | 3694 |
| Gene | FGG |
| Long gene name | fibrinogen gamma chain |
| Synonyms gene name | fibrinogen, gamma polypeptide |
| Locus | 4q32, 1 |
| Discovery year | 2001-06-22 |
| Entrez gene record | 2266 |
| RefSeq identity | NM_021870 |
| Classification | Endogenous ligands Fibrinogen C domain containing |
| Havana BLAST/BLAT | OTTHUMG00000150329 |
| Locus Specific Databases | A Database For Human Fibrinogen Variants LRG_585 |