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Fibrinogen beta chain Antibody (FGB)

Fibrinogen beta chain Antibody (FGB) size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenFibrinogen beta chain (FGB)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
NotesOptimal dilution of the Fibrinogen beta chain antibody should be determined by the researcher
Added buffer025% sodium azide, 5% BSA and 0, Lyophilized from 1X Phosphate Buffered Saline (PBS) with 2
Intented useThis antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P02675
PurityAntigen affinity
Description Alternatively spliced transcript variants encoding different isoforms have been found for this gene, Following vascular injury, In addition, Mutations in this gene lead to several disorders, The protein encoded by this gene is the beta component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains, and are mitogens for several cell types, display vasoconstrictor and chemotactic activities, dysfibrinogenemia, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots, hypodysfibrinogenemia and thrombotic tendency, including afibrinogenemia, is also known as FGB, mapped to 4q31, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, 3, Fibrinogen beta chain
ImmunogenAmino acids 193-225 (TNLRVLRSILENLRSKIQKLESDVSAQMEYCRT-human) were used as the immunogen for the Fibrinogen beta chain antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Fibrinogen beta chain antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetFibrinogen beta chain (FGB)
Short nameFibrinogen beta chain Antibody (FGB)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFibrinogen b epitope (Antibody to) (fibrinogen beta chain)
Alternative techniqueantibodies
Alternative to gene target Extracellular, FGB and IDBG-42021 and ENSG00000171564 and 2244, FGB and IDBG-628961 and ENSBTAG00000022120 and 510522, Fgb and IDBG-154611 and ENSMUSG00000033831 and 110135, HEL-S-78p, bridging, bridging and also this GO :0050839: cell adhesion molecule binding and also this GO :0051087: chaperone binding, bridging and molecular function this GO :0031091 and platelet alpha granule and cellular component this GO :0031093 and platelet alpha granule lumen and cellular component this GO :0034116 and positive regulation of heterotypic cell-cell adhesion and biological process this GO :0043623 and cellular protein complex assembly and biological process this GO :0044320 and cellular response to leptin stimulus and biological process this GO :0045907 and positive regulation of vasoconstriction and biological process this GO :0045921 and positive regulation of exocytosis and biological process this GO :0050714 and positive regulation of protein secretion and biological process this GO :0050839 and cell adhesion molecule binding and molecular function this GO :0051087 and chaperone binding and molecular function this GO :0051258 and protein polymerization and biological process this GO :0051592 and response to calcium ion and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070374 and positive regulation of ERK1 and ERK2 cascade and biological process this GO :0070527 and platelet aggregation and biological process this GO :0071347 and cellular response to interleukin-1 and biological process this GO :0072562 and blood microparticle and cellular component this GO :0090277 and positive regulation of peptide hormone secretion and biological process this GO :1900026 and positive regulation of substrate adhesion-dependent cell spreading and biological process this GO :1902042 and negative regulation of extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :2000352 and negative regulation of endothelial cell apoptotic process and biological process, protein binding, this GO :0002576 and platelet degranulation and biological process this GO :0005102 and receptor binding and molecular function this GO :0005198 and structural molecule activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005577 and fibrinogen complex and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005938 and cell cortex and cellular component this GO :0007160 and cell-matrix adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007596 and blood coagulation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0030168 and platelet activation and biological process this GO :0030198 and extracellular matrix organization and biological process this GO :0030674 and protein binding, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0005198: structural molecule activity and also this GO :0005515: protein binding and also this GO :0030674: protein binding, this GO :0005198: structural molecule activity, this GO :0005515: protein binding, this GO :0030674: protein binding, this GO :0050839: cell adhesion molecule binding, this GO :0051087: chaperone binding, fibrinogen beta chain
Identity 3662
Gene FGB
Long gene name fibrinogen beta chain
Synonyms gene name B beta polypeptide , fibrinogen
Locus 4q31, 3
Discovery year 2001-06-22
Entrez gene record 2244
RefSeq identity NM_005141
Classification Endogenous ligands Fibrinogen C domain containing
Havana BLAST/BLAT OTTHUMG00000150331
Locus Specific Databases A Database For Human Fibrinogen Variants LRG_558

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