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FIG4/SAC3 Antibody

FIG4/SAC3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFIG4/SAC3 Primary Polyclonal Antibody
Also known asFIG4/SAC3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFIG4/SAC3
SpecificityThis is a highly specific antibody against FIG4/SAC3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FIG4
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration, Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), Unlike CMT4J, both of which negatively affect the nervous system, causing paralysis and, death, ultimately, FIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ALS11, FIG4_HUMAN, Fig4, KIAA0274, Phosphatidylinositol 3, Phosphatidylinositol 3, Polyphosphoinositide phosphatase, SAC domain containing protein 3, SAC domain-containing protein 3, SAC3, hSac3, 5 bisphosphate 5 phosphatase, 5-bisphosphate 5-phosphatase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFIG4/SAC3
Short nameFIG4/SAC3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFIG4/SAC3 (Antibody to)
Alternative techniqueantibodies
Identity 16873
Gene FIG4
Long gene name FIG4 phosphoinositide 5-phosphatase
Synonyms gene KIAA0274
Synonyms gene name KIAA0274 FIG4 homolog (S, SAC1 lipid phosphatase domain containing (S, cerevisiae) , cerevisiae) FIG4 homolog
Synonyms SAC3 hSac3 dJ249I4, 1 ALS11 CMT4J
Locus 6q21
Discovery year 2003-11-26
GenBank acession D87464
Entrez gene record 9896
Pubmed identfication 9039502 11274189 17572665
RefSeq identity NM_014845
Classification Phosphoinositide phosphatases
Havana BLAST/BLAT OTTHUMG00000015352
Locus Specific Databases LRG_241

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