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Filaggrin Antibody

Filaggrin Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenFilaggrin
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions1-0, 5-1ug/ml, 5ug/ml, IHC (Paraffin): 0, Western blot: 0
NotesOptimal dilution of the Filaggrin antibody should be determined by the researcher
Intented useThis Filaggrin antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P20930
PurityAntigen affinity
Description It is initially synthesized as a polyprotein precursor, Mutations in this gene are associated with ichthyosis vulgaris, The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis, and is subsequently proteolytically processed into individual functional filaggrin molecules, profilaggrin (consisting of multiple filaggrin units of 324 aa each), profillagrin is encoded by the FLG gene, which is localized in keratohyalin granules, which is part of the S100 fused-type protein (SFTP) family within the epidermal differentiation complex on chromosome 1q21, In humans
ImmunogenAmino acids 1-261 of human Filaggrin were used as the immunogen for the Filaggrin antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Filaggrin antibody may be kept for up to one month refrigerated at +4 degrees C, After reconstitution, For long-term
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetFilaggrin
Short nameFilaggrin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFilaggrin (Antibody to)
Alternative techniqueantibodies
Identity 3748
Gene FLG
Long gene name filaggrin
Locus 1q21, 3
Discovery year 1989-10-18
GenBank acession XM_048104
Entrez gene record 2312
Pubmed identfication 2740331 2248957 16444271
RefSeq identity NM_002016
Classification S100 fused type protein family EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000012202
Locus Specific Databases LRG_1028

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