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FIP1L1 Antibody

FIP1L1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFIP1L1 Primary Polyclonal Antibody
Also known asFIP1L1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFIP1L1
SpecificityThis is a highly specific antibody against FIP1L1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FIP1L1
Gene ID number81608
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), FIP1L1 (FIP1-like 1), FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition, Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events, This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail, Within the complex, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage, also known as Pre-mRNA 3'-end-processing factor FIP1, is a 594 amino acid nuclear protein that is a component of the CPSF complex, The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FIP1, FIP1 like 1, FIP1 like 1 S cerevisiae, FIP1_HUMAN, FLJ33619, Factor interacting with PAP, Pre mRNA 3 end processing factor FIP1, RHE, Rearranged in hypereosinophilia, hFip 1, hFip1, DKFZp586K0717
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFIP1L1
Short nameFIP1L1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFIP1L1 (Antibody to)
Alternative techniqueantibodies
Identity 19124
Gene FIP1L1
Long gene name factor interacting with PAPOLA and CPSF1
Synonyms gene name FIP1 like 1 (S, cerevisiae) FIP1L1 cleavage and polyadenylation specific factor subunit
Synonyms DKFZp586K0717 FIP1
Locus 4q12
Discovery year 2003-03-03
GenBank acession AF161429
Entrez gene record 81608
Pubmed identfication 11230166 14749727
RefSeq identity NM_030917
Havana BLAST/BLAT OTTHUMG00000128701

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