Name : FIP1L1 Antibody, ALEXA FLUOR 555
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN1706922572
| Long name | ALEXA FLUOR 555 Conjugated, FIP1L1 Polyclonal Antibody |
| Also known as | Anti-FIP1L1 PAb ALEXA FLUOR 555 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 555, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FIP1L1 |
| Specificity | This is a highly specific antibody against FIP1L1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FIP1L1 |
| Gene ID Number | 81608 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), FIP1L1 (FIP1-like 1), FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition, Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events, This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail, Within the complex, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage, also known as Pre-mRNA 3'-end-processing factor FIP1, is a 594 amino acid nuclear protein that is a component of the CPSF complex, The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 553nm/568nm |
| Synonyms | DKFZp586K0717 FIP1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 555, Alexa Fluor |
| Gene target | FIP1L1 |
| Short name | FIP1L1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 555 |
| Alternative name | ALEXA FLUOR 555, FIP1L1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 19124 |
| Gene | FIP1L1 |
| Long gene name | factor interacting with PAPOLA and CPSF1 |
| Synonyms gene name | FIP1 like 1 (S, cerevisiae) FIP1L1 cleavage and polyadenylation specific factor subunit |
| Locus | 4q12 |
| Discovery year | 2003-03-03 |
| GenBank acession | AF161429 |
| Entrez gene record | 81608 |
| Pubmed identfication | 11230166 14749727 |
| RefSeq identity | NM_030917 |
| Havana BLAST/BLAT | OTTHUMG00000128701 |