Name : FIP1L1 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN9610069832
| Long name | Biotin Conjugated, FIP1L1 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FIP1L1 |
| Specificity | This is a highly specific antibody against FIP1L1 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human FIP1L1 |
| Gene ID number | 81608 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), FIP1L1 (FIP1-like 1), FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition, Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events, This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail, Within the complex, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage, also known as Pre-mRNA 3'-end-processing factor FIP1, is a 594 amino acid nuclear protein that is a component of the CPSF complex, The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | DKFZp586K0717 FIP1 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FIP1L1 Conjugated |
| Short name | Conjugated, FIP1L1 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, FIP1L1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 19124 |
| Gene | FIP1L1 |
| Long gene name | factor interacting with PAPOLA and CPSF1 |
| Synonyms gene name | FIP1 like 1 (S, cerevisiae) FIP1L1 cleavage and polyadenylation specific factor subunit |
| Locus | 4q12 |
| Discovery year | 2003-03-03 |
| GenBank acession | AF161429 |
| Entrez gene record | 81608 |
| Pubmed identfication | 11230166 14749727 |
| RefSeq identity | NM_030917 |
| Havana BLAST/BLAT | OTTHUMG00000128701 |