Filters

FIP1L1 Antibody, Biotin Conjugated

FIP1L1 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, FIP1L1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFIP1L1
SpecificityThis is a highly specific antibody against FIP1L1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FIP1L1
Gene ID number81608
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background FIP1 (Factor interacting with PAP) and RHE (Rearranged in hypereosinophilia), FIP1L1 (FIP1-like 1), FIP1L1 contributes to the poly(A) recognition and stimulates poly(A) addition, Fusion of the genes encoding FIP1L1 and PDGFRA due to an interstitial deletion on chromosome 4q12 is the cause of hypereosinophilia syndrome, There are three isoforms of FIP1L1 that are produced as a result of alternative splicing events, This complex recognizes the AAUAAA signal sequence and interacts with poly(A) polymerase to process and add to the poly(A) tail, Within the complex, a rare blood disorder characterized by continuous overproduction of eosinophils in the bone marrow that leads to tissue infiltration and organ damage, also known as Pre-mRNA 3'-end-processing factor FIP1, is a 594 amino acid nuclear protein that is a component of the CPSF complex, The Component of the Cleavage and Polyadenylation Specificity Factor (CPSF) complex plays an important role in the 3'-end formation of pre-mRNA
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms DKFZp586K0717 FIP1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFIP1L1 Conjugated
Short name Conjugated, FIP1L1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, FIP1L1 (Antibody to)
Alternative techniqueantibodies
Identity 19124
Gene FIP1L1
Long gene name factor interacting with PAPOLA and CPSF1
Synonyms gene name FIP1 like 1 (S, cerevisiae) FIP1L1 cleavage and polyadenylation specific factor subunit
Locus 4q12
Discovery year 2003-03-03
GenBank acession AF161429
Entrez gene record 81608
Pubmed identfication 11230166 14749727
RefSeq identity NM_030917
Havana BLAST/BLAT OTTHUMG00000128701

Subscribe to our Newsletter