Name : FKBP38 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4029586324
| Long name | FKBP38 Primary Polyclonal Antibody |
| Also known as | FKBP38 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | FKBP38 |
| Specificity | This is a highly specific antibody against FKBP38 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FKBP38 |
| Gene ID number | 23770 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Does not bind and inhibit calcineurin, Forms heterodimer with calmodulin, Highest levels seen in the brain, Homomultimers or heteromultimers (Potential), Interacts with HCV NS5A, Interacts with ZFYVE27, Seems to act as a chaperone for BCL2, The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets, The active form of FKBP8 may therefore play a role in the regulation of apoptosis, When activated by calmodulin and calcium, interacts with the BH4 domain of BCL2 and weakly with BCLX isoform Bcl-X(L), may negatively regulate ZFYVE27 phosphorylation, targets it to the mitochondria and modulates its phosphorylation state, which becomes active when bound to calmodulin and calcium, Constitutively inactive PPiase, Tissue specificity: Widely expressed |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 38 kDa FK506-binding protein, 38 kDa FKBP, 38kDa, 38kDa, 38kDa antibody FK506 binding protein 8, FK506 binding protein, FK506 binding protein 8, FK506-binding protein 8, FKBP 38, FKBP-38, FKBP-8, FKBP8, FKBP8_HUMAN, FKBPR38, PPIase FKBP8, Peptidyl-prolyl cis-trans isomerase FKBP8, Rotamase, Sam11, hFKBP38, 38 kDa FK 506 binding protein homolog |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FKBP38 |
| Short name | FKBP38 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | FKBP38 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3724 |
| Gene | FKBP8 |
| Long gene name | FK506 binding protein 8 |
| Synonyms gene name | 38kDa , FK506-binding protein 8 (38kD) FK506 binding protein 8 |
| Synonyms | FKBP38 FKBPr38 |
| Synonyms name | FK506-binding protein 8 (38kD) |
| Locus | 19p13, 11 |
| Discovery year | 1999-10-28 |
| GenBank acession | L37033 |
| Entrez gene record | 23770 |
| Pubmed identfication | 7543869 |
| RefSeq identity | NM_012181 |
| Classification | FKBP prolyl isomerases Tetratricopeptide repeat domain containing |
| Havana BLAST/BLAT | OTTHUMG00000183368 |