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FKBP38 Antibody, Biotin Conjugated

FKBP38 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, FKBP38 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFKBP38
SpecificityThis is a highly specific antibody against FKBP38
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FKBP38
Gene ID number23770
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Does not bind and inhibit calcineurin, Forms heterodimer with calmodulin, Highest levels seen in the brain, Homomultimers or heteromultimers (Potential), Interacts with HCV NS5A, Interacts with ZFYVE27, Seems to act as a chaperone for BCL2, The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets, The active form of FKBP8 may therefore play a role in the regulation of apoptosis, When activated by calmodulin and calcium, interacts with the BH4 domain of BCL2 and weakly with BCLX isoform Bcl-X(L), may negatively regulate ZFYVE27 phosphorylation, targets it to the mitochondria and modulates its phosphorylation state, which becomes active when bound to calmodulin and calcium, Constitutively inactive PPiase, Tissue specificity: Widely expressed
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FKBP38 FKBPr38
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFKBP38 Conjugated
Short name Conjugated, FKBP38 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, FKBP38 (Antibody to)
Alternative techniqueantibodies
Identity 3724
Gene FKBP8
Long gene name FK506 binding protein 8
Synonyms gene name 38kDa , FK506-binding protein 8 (38kD) FK506 binding protein 8
Synonyms name FK506-binding protein 8 (38kD)
Locus 19p13, 11
Discovery year 1999-10-28
GenBank acession L37033
Entrez gene record 23770
Pubmed identfication 7543869
RefSeq identity NM_012181
Classification FKBP prolyl isomerases Tetratricopeptide repeat domain containing
Havana BLAST/BLAT OTTHUMG00000183368

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