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FKBP38 Antibody, FITC Conjugated

FKBP38 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, FKBP38 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFKBP38
SpecificityThis is a highly specific antibody against FKBP38
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FKBP38
Gene ID number23770
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Does not bind and inhibit calcineurin, Forms heterodimer with calmodulin, Highest levels seen in the brain, Homomultimers or heteromultimers (Potential), Interacts with HCV NS5A, Interacts with ZFYVE27, Seems to act as a chaperone for BCL2, The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets, The active form of FKBP8 may therefore play a role in the regulation of apoptosis, When activated by calmodulin and calcium, interacts with the BH4 domain of BCL2 and weakly with BCLX isoform Bcl-X(L), may negatively regulate ZFYVE27 phosphorylation, targets it to the mitochondria and modulates its phosphorylation state, which becomes active when bound to calmodulin and calcium, Constitutively inactive PPiase, Tissue specificity: Widely expressed
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FKBP38 FKBPr38
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFKBP38 Conjugated
Short name FITC Conjugated, FKBP38 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, FKBP38 (Antibody to)
Alternative techniqueantibodies
Identity 3724
Gene FKBP8
Long gene name FK506 binding protein 8
Synonyms gene name 38kDa , FK506-binding protein 8 (38kD) FK506 binding protein 8
Synonyms name FK506-binding protein 8 (38kD)
Locus 19p13, 11
Discovery year 1999-10-28
GenBank acession L37033
Entrez gene record 23770
Pubmed identfication 7543869
RefSeq identity NM_012181
Classification FKBP prolyl isomerases Tetratricopeptide repeat domain containing
Havana BLAST/BLAT OTTHUMG00000183368

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