Filters

FKBP51 Antibody

FKBP51 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFKBP51 Primary Polyclonal Antibody
Also known asFKBP51 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFKBP51
SpecificityThis is a highly specific antibody against FKBP51
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FKBP51
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen FK506 and rapamycin (1), FKBP12, FKBP51 and FKBP52, FKBP51 and FKBP52 are two highly related proteins (5, FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids (5), FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, FKBP52, Several related immunophilins, The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGF?type I receptor, and by blocking T-cell activation and proliferation (7), and following ligand binding, are characterized as cytosolic FK506-binding proteins, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6, known also as FKBP-59 or heat shock protein 56, such as cyclosporin, they functionally inhibit the phosphatase activity of calcineurin (2, where it stabilizes the inactive conformation of the receptor and blocks the activation of the TGF?pathway (4), 3), 6), 8), The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 51 kDa FK506 binding protein, 51 kDa FK506 binding protein 5, 51 kDa FK506-binding protein, 51 kDa FKBP, 54 kDa progesterone receptor associated immunophilin, 54 kDa progesterone receptor-associated immunophilin, AIG 6, AIG6, Androgen regulated protein 6, Androgen-regulated protein 6, FF1 antigen, FK506 binding protein 5, FK506-binding protein 5, FKBP 51, FKBP 54, FKBP-5, FKBP-51, FKBP5, FKBP54, FKBP5_HUMAN, HSP90 binding immunophilin, HSP90-binding immunophilin, MGC111006, OTTHUMP00000016268, P54 antibody Peptidyl prolyl cis trans isomerase, PPIase, PPIase FKBP5, Peptidyl-prolyl cis-trans isomerase FKBP5, Peptidylprolyl cis trans isomerase, Ptg 10, Ptg10, Rotamase, T cell FK506 binding protein, FKBP 5
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFKBP51
Short nameFKBP51 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFKBP51 (Antibody to)
Alternative techniqueantibodies
Identity 3721
Gene FKBP5
Long gene name FK506 binding protein 5
Synonyms gene name FK506-binding protein 5
Synonyms FKBP51 FKBP54 PPIase P54 Ptg-10
Locus 6p21, 31
Discovery year 1997-06-09
GenBank acession U42031
Entrez gene record 2289
Pubmed identfication 9001212
Classification FKBP prolyl isomerases Tetratricopeptide repeat domain containing
Havana BLAST/BLAT OTTHUMG00000014576

Similar products

Subscribe to our Newsletter