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FKBP51 Antibody, ALEXA FLUOR 555

FKBP51 Antibody, ALEXA FLUOR 555 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, FKBP51 Polyclonal Antibody
Also known asAnti-FKBP51 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFKBP51
SpecificityThis is a highly specific antibody against FKBP51
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FKBP51
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen FK506 and rapamycin (1), FKBP12, FKBP51 and FKBP52, FKBP51 and FKBP52 are two highly related proteins (5, FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids (5), FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, FKBP52, Several related immunophilins, The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGF?type I receptor, and by blocking T-cell activation and proliferation (7), and following ligand binding, are characterized as cytosolic FK506-binding proteins, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6, known also as FKBP-59 or heat shock protein 56, such as cyclosporin, they functionally inhibit the phosphatase activity of calcineurin (2, where it stabilizes the inactive conformation of the receptor and blocks the activation of the TGF?pathway (4), 3), 6), 8), The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms FKBP51 FKBP54 PPIase P54 Ptg-10
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetFKBP51
Short nameFKBP51 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, FKBP51 (Antibody to)
Alternative techniqueantibodies
Identity 3721
Gene FKBP5
Long gene name FK506 binding protein 5
Synonyms gene name FK506-binding protein 5
Locus 6p21, 31
Discovery year 1997-06-09
GenBank acession U42031
Entrez gene record 2289
Pubmed identfication 9001212
Classification FKBP prolyl isomerases Tetratricopeptide repeat domain containing
Havana BLAST/BLAT OTTHUMG00000014576

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