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FKBP51 Antibody, HRP Conjugated

FKBP51 Antibody, HRP Conjugated size: 0.1ml 350

Price 350
Size 0.1ml
Long name HRP Conjugated, FKBP51 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationHRP Conjugated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFKBP51
SpecificityThis is a highly specific antibody against FKBP51
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human FKBP51
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background FK506 and rapamycin (1), FKBP12, FKBP51 and FKBP52, FKBP51 and FKBP52 are two highly related proteins (5, FKBP51 is predominantly expressed in T cells and is induced by glucocorticoids (5), FKBP51 mediates the effects of FK506 and rapamycin by inhibiting intracellular calcineurin activity, FKBP52, Several related immunophilins, The ubiquitously expressed FKBP12 also associates with the cytoplasmic domain of the TGF?type I receptor, and by blocking T-cell activation and proliferation (7), and following ligand binding, are characterized as cytosolic FK506-binding proteins, is expressed in a variety of tissues and can also associate with the heat shock protein (hsp90) in mature steroid receptor complexes (6, known also as FKBP-59 or heat shock protein 56, such as cyclosporin, they functionally inhibit the phosphatase activity of calcineurin (2, where it stabilizes the inactive conformation of the receptor and blocks the activation of the TGF?pathway (4), 3), 6), 8), The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% Gentamicin, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FKBP51 FKBP54 PPIase P54 Ptg-10
Properties Also monoclonal HRP conjugates are often used for Western Blot, HRP conjugates are often primary rabbit polyclonal antibodies couples to the , found in the roots of , (HRP), C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°, enzyme , horseradish, horseradish peroxidase 
Gene targetFKBP51 Conjugated
Short name Conjugated, FKBP51 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelHRP
Alternative name horseradish peroxidase coupled, FKBP51 (Antibody to)
Alternative techniqueantibodies
Identity 3721
Gene FKBP5
Long gene name FK506 binding protein 5
Synonyms gene name FK506-binding protein 5
Locus 6p21, 31
Discovery year 1997-06-09
GenBank acession U42031
Entrez gene record 2289
Pubmed identfication 9001212
Classification FKBP prolyl isomerases Tetratricopeptide repeat domain containing
Havana BLAST/BLAT OTTHUMG00000014576

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