| Long name | FLI1 Primary Polyclonal Antibody |
| Also known as | FLI1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | FLI1 |
| Specificity | This is a highly specific antibody against FLI1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FLI1 |
| Gene ID number | 2313 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | A highly malignant, Ewing sarcoma represents the less differentiated form of the tumors, It belongs to the Ewing sarcoma family of tumors, Note=A chromosomal aberration involving FLI1 is found in patients with Erwing sarcoma, Recognizes the DNA sequence 5'-C[CA]GGAAGT-3', They are considered neural tumors derived from cells of the neural crest, Translocation t(11, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents, 22)(q24, Involvement in diseaseDefects in FLI1 are a cause of Ewing sarcoma (ES) , Sequence-specific transcriptional activator, q12) with EWSR1 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | EWSR 2, EWSR2, Ewing Sarcoma breakpoint region 2, FLI 1, FLI 1 proto oncogene, FLI1, FLI1 EWS fusion gene, FLI1 proto oncogene, FLI1_HUMAN, Friend leukemia integration 1 transcription factor, Friend leukemia virus integration 1, Proto-oncogene Fli-1, SIC 1, SIC1, Transcription factor ERGB, Viral integration region FLI1, ERGB transcription factor |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FLI1 |
| Short name | FLI1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | Friend leukemia virus integration 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BT, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0007599 and hemostasis and biological process this GO :0008015 and blood circulation and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0030154 and cell differentiation and biological process this GO :0035855 and megakaryocyte development and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process, EWSR2 and SIC-1, FLI1 and IDBG-75950 and ENSG00000151702 and 2313, Fli1 and IDBG-147469 and ENSMUSG00000016087 and 14247, nuclei, sequence-specific DNA binding, this GO :0000978 and RNA polymerase II core promoter proximal region sequence-specific DNA binding and molecular function this GO :0000980 and RNA polymerase II distal enhancer sequence-specific DNA binding and molecular function this GO :0000981 and sequence-specific DNA binding RNA polymerase II transcription factor activity and molecular function this GO :0001077 and RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and molecular function this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0006355 and regulation of transcription, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding, this GO :0000978: RNA polymerase II core promoter proximal region sequence-specific DNA binding and also this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding and also this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity and also this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription and also this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0043565: sequence-specific DNA binding, this GO :0000980: RNA polymerase II distal enhancer sequence-specific DNA binding, this GO :0000981: sequence-specific DNA binding RNA polymerase II transcription factor activity, this GO :0001077: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, this GO :0003677: DNA binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0043565: sequence-specific DNA binding, 67771 and IDBG-642793 and ENSBTAG00000008283 and 529124, Friend leukemia virus integration 1 |
| Identity | 3749 |
| Gene | FLI1 |
| Long gene name | ETS transcription factor , Fli-1 proto-oncogene |
| Synonyms gene name | Friend leukemia virus integration 1 |
| Synonyms | SIC-1 EWSR2 |
| Locus | 11q24, 3 |
| Discovery year | 1991-06-05 |
| GenBank acession | M98833 |
| Entrez gene record | 2313 |
| Pubmed identfication | 1765382 |
| RefSeq identity | NM_002017 |
| Classification | ETS transcription factor family |
| Havana BLAST/BLAT | OTTHUMG00000165792 |
| Locus Specific Databases | LRG_646 |
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