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FLIP Antibody

FLIP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFLIP Primary Polyclonal Antibody
Also known asFLIP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFLIP
SpecificityThis is a highly specific antibody against FLIP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range462-480/480
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CASP8 and FADD-like apoptosis regulator subunit p12 (Potential)
Gene ID number8837
Swiss ProtO15519
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex, Acts as an inhibitor of TNFRSF6 mediated apoptosis, Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis, Lacks enzymatic (caspase) activity, Apoptosis regulator protein which may function as a crucial link between cell survival and cell death pathways in mammalian cells
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CASP8 and FADD-like apoptosis regulator, CASP8AP1, CFLAR, CLARP, Caspase homolog, Caspase-eight-related protein, Caspase-like apoptosis regulatory protein, Casper, Cellular FLICE-like inhibitory protein, FADD-like antiapoptotic molecule 1, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, Inhibitor of FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS, CASH
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFLIP
Short nameFLIP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFLIP (Antibody to)
Alternative techniqueantibodies
Identity 1876
Gene CFLAR
Long gene name CASP8 and FADD like apoptosis regulator
Synonyms gene CASP8AP1
Synonyms gene name CASP8 and FADD-like apoptosis regulator
Synonyms CASH Casper CLARP FLAME FLIP I-FLICE MRIT c-FLIP
Locus 2q33, 1
Discovery year 1999-05-07
GenBank acession AF005774
Entrez gene record 8837
Pubmed identfication 9208847 9217161
RefSeq identity NM_003879
Classification Endogenous ligands Death effector domain containing Death inducing signaling complex
Havana BLAST/BLAT OTTHUMG00000132819

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