Name : FLT-3 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN3574903181
| Long name | ALEXA FLUOR 488 Conjugated, FLT-3 Polyclonal Antibody |
| Also known as | Anti-FLT-3 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FLT-3 |
| Specificity | This is a highly specific antibody against FLT-3 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FLT-3 |
| Gene ID Number | 2322 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B, FER, Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways, PLCG1, PTPN11/SHP-2, PTPN6/SHP, Promotes activation of RAS signaling and phosphorylation of downstream kinases, Promotes phosphorylation of FES, Promotes phosphorylation of SHC1 and AKT1, and STAT5A and/or STAT5B, and activation of the downstream effector MTOR, including MAPK1/ERK2 and/or MAPK3/ERK1, proliferation and survival of hematopoietic progenitor cells and of dendritic cells, Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | FL cytokine receptor, FLT3_HUMAN, FMS like tyrosine kinase 3, Fetal liver kinase 2, Flk 2, Flk2, Flt 3, Flt3, Fms related tyrosine kinase 3, Growth factor receptor tyrosine kinase type III, Stem cell tyrosine kinase 1, Stk 1, Stk1, Tyrosine protein kinase receptor FLT3, CD135 antigen |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the FLT-3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | FLT-3 |
| Short name | FLT-3 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, FLT-3 (Antibody to) |
| Alternative technique | antibodies |