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FLT-3 Antibody, Biotin Conjugated

FLT-3 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, FLT-3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFLT-3
SpecificityThis is a highly specific antibody against FLT-3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceKLH conjugated synthetic peptide derived from human FLT-3
Gene ID number2322
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B, FER, Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways, PLCG1, PTPN11/SHP-2, PTPN6/SHP, Promotes activation of RAS signaling and phosphorylation of downstream kinases, Promotes phosphorylation of FES, Promotes phosphorylation of SHC1 and AKT1, and STAT5A and/or STAT5B, and activation of the downstream effector MTOR, including MAPK1/ERK2 and/or MAPK3/ERK1, proliferation and survival of hematopoietic progenitor cells and of dendritic cells, Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FL cytokine receptor, FLT3_HUMAN, FMS like tyrosine kinase 3, Fetal liver kinase 2, Flk 2, Flk2, Flt 3, Flt3, Fms related tyrosine kinase 3, Growth factor receptor tyrosine kinase type III, Stem cell tyrosine kinase 1, Stk 1, Stk1, Tyrosine protein kinase receptor FLT3, CD135 antigen
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFLT-3 Conjugated
Short name Conjugated, FLT-3 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, FLT-3 (Antibody to)
Alternative techniqueantibodies

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