Name : FLT-3 Antibody, Cy5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN9568029355
| Long name | Cy5 Conjugated, FLT-3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FLT-3 |
| Specificity | This is a highly specific antibody against FLT-3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human FLT-3 |
| Gene ID number | 2322 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B, FER, Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways, PLCG1, PTPN11/SHP-2, PTPN6/SHP, Promotes activation of RAS signaling and phosphorylation of downstream kinases, Promotes phosphorylation of FES, Promotes phosphorylation of SHC1 and AKT1, and STAT5A and/or STAT5B, and activation of the downstream effector MTOR, including MAPK1/ERK2 and/or MAPK3/ERK1, proliferation and survival of hematopoietic progenitor cells and of dendritic cells, Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 625, 650nm/670nm |
| Synonyms | FL cytokine receptor, FLT3_HUMAN, FMS like tyrosine kinase 3, Fetal liver kinase 2, Flk 2, Flk2, Flt 3, Flt3, Fms related tyrosine kinase 3, Growth factor receptor tyrosine kinase type III, Stem cell tyrosine kinase 1, Stk 1, Stk1, Tyrosine protein kinase receptor FLT3, CD135 antigen |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FLT-3 Conjugated |
| Short name | Conjugated, FLT-3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy5 |
| Alternative name | cyanine 5 coupled, FLT-3 (Antibody to) |
| Alternative technique | antibodies |