Name : Flt3 ligand Antibody
Supplier : NJS POLY
Price :389
SKU : GEN4658870118
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | Flt3 ligand |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | WB |
| Recommended dilutions | 5-1ug/ml, Western blot: 0 |
| Notes | Titration of the Flt3 ligand antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This Flt3 ligand antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P49771 |
| Purity | Antigen affinity |
| Description | Assays of C-terminally truncated FL proteins confirmed that the N-terminal half conferred FL activity, Depletion of the Pi3k -Mtor negative regulator Pten facilitated FLT3L-driven DC development in culture, FLT3L is a hematopoietic four helical bundlecytokine, FLT3L stimulates the proliferation and differentiation of various blood cell progenitors, Hannum et al, In synergy with other growth factors, It is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1), Lyman et al, The protein controls the development of DCs and is particularly important for plasmacytoid DCs and CD8-positive classical DCs and their CD103-positive tissue counterparts, also called FL or FLT3L, is a protein which in humans is encoded by the FLT3LG gene, (1993) found that it stimulated proliferation of hematopoietic progenitor cells isolated from mouse fetal liver or adult mouse bone marrow, (1994) concluded that FLT3L enhances the response of stem and primitive progenitor cells to other growth factors to generate all myeloid lineages except erythroid cells, Flt3 (FMS-Related Tyrosine Kinase 3) Ligand |
| Immunogen | An amino acid sequence from the C-terminus of human Flt3 ligand (HWQRTRRRTPRPGEQ) was used as the immunogen for this Flt3 ligand antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the Flt3 ligand antibody can be stored for up to one month at 4oC, After reconstitution |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | Flt3 ligand |
| Short name | Flt3 ligand Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | fms-related tyrosine kinase 3 ligand (Antibody to) |
| Alternative technique | antibodies |