Name : FMO3 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN6090817707
| Long name | FITC Conjugated, FMO3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FMO3 |
| Specificity | This is a highly specific antibody against FMO3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human FMO3 |
| Gene ID number | 2328 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Defects in the FMO3 gene are the primary cause of trimethylaminuria (TMAuria), FMO1-5, FMO3 acts on a variety of xenobiotics to catalyze oxidative digestion, FMO3 is a hepatic microsomal enzyme that oxygenates soft nucleophiles such as secondary and tertiary amines, Genetic mutations in FMO3 lead to the N-oxidation of amino-trimethylamine derived from food products, Located in the liver, Through its N-oxygenase capabilities, an inborn error of metabolism associated with a fishy body odor emitting from sweat, that are major enzymatic oxidants involved in the metabolism of various therapeutics, thus producing the malodor associated with TMAuria, urine and breath, The Flavin containing monooxygenase family consists of five gene products |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FMO3 Conjugated |
| Short name | FITC Conjugated, FMO3 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, FMO3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3771 |
| Gene | FMO3 |
| Long gene name | flavin containing monooxygenase 3 |
| Locus | 1q24, 3 |
| Discovery year | 1992-10-16 |
| GenBank acession | BC032016 |
| Entrez gene record | 2328 |
| Pubmed identfication | 8486388 9417913 |
| RefSeq identity | NM_006894 |
| Havana BLAST/BLAT | OTTHUMG00000035505 |
| Locus Specific Databases | The Homo sapients FMO3 Allelic Variant Database |