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FMR2/AFF2 Antibody

FMR2/AFF2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFMR2/AFF2 Antibody
Also known asFMR2/AFF2 Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFMR2/AFF2
SpecificityThis is a highly specific antibody against FMR2/AFF2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human AFF2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, Expressed in the brain, FMR2 exists as two isoforms produced by alternative splicing, Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site, an X-linked form of mental retardation, compared to six to thirty-five copies of the GCC repeat in a normal individual, placenta and lung, FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AF4/FMR2 family, AFF2, AFF2_HUMAN, FMR2, FMR2P, FRAXE, Fragile X E mental retardation syndrome protein, Fragile X mental retardation 2 protein, MRX2, OX19, Protein FMR-2, Protein Ox19, fragile X mental retardation 2, fragile X mental retardation gene associated with FRAXE, member 2, mild or borderline mental retardation, AF4/FMR2 family member 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFMR2/AFF2
Short nameFMR2/AFF2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFMR2/AFF2 (Antibody to)
Alternative techniqueantibodies
Identity 3776
Gene AFF2
Long gene name AF4/FMR2 family member 2
Synonyms gene FMR2
Synonyms gene name fragile X mental retardation 2 AF4/FMR2 family, member 2
Synonyms FRAXE
Locus Xq28
Discovery year 2005-06-27
GenBank acession U48436
Entrez gene record 2334
RefSeq identity NM_002025
Classification AF4/FMR2 family Super elongation complex
Havana BLAST/BLAT OTTHUMG00000022613
Locus Specific Databases Mental Retardation database

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