Filters

FMR2/AFF2 Antibody, Biotin Conjugated

FMR2/AFF2 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, FMR2/AFF2 Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFMR2/AFF2
SpecificityThis is a highly specific antibody against FMR2/AFF2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human AFF2
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Defects in the gene that encodes FMR2 have been found to be a cause of FRAXE, Expressed in the brain, FMR2 exists as two isoforms produced by alternative splicing, Individuals expressing the FRAXE site also have more than two-hundred copies of a GCC repeat adjacent to CpG island, It is believed that loss of FMR2 expression causes this GCC expansion of the FRAXE site, an X-linked form of mental retardation, compared to six to thirty-five copies of the GCC repeat in a normal individual, placenta and lung, FMR2 is a 1311 amino acid nuclear protein belonging to the AF4 family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms FRAXE
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFMR2/AFF2 Conjugated
Short name Conjugated, FMR2/AFF2 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, FMR2/AFF2 (Antibody to)
Alternative techniqueantibodies
Identity 3776
Gene AFF2
Long gene name AF4/FMR2 family member 2
Synonyms gene FMR2
Synonyms gene name fragile X mental retardation 2 AF4/FMR2 family, member 2
Locus Xq28
Discovery year 2005-06-27
GenBank acession U48436
Entrez gene record 2334
RefSeq identity NM_002025
Classification AF4/FMR2 family Super elongation complex
Havana BLAST/BLAT OTTHUMG00000022613
Locus Specific Databases Mental Retardation database

Subscribe to our Newsletter