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FMRP (Ser500) Antibody

FMRP (Ser500) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFMRP (Ser500) Primary Polyclonal Antibody
Also known asFMRP (Ser500) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFMRP Ser500
SpecificityThis is a highly specific antibody against FMRP Ser500
Modification(s)Phosphorylation
Modification site(s)Ser500
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range480-530/632
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500
Gene ID number2332
Swiss ProtQ06787
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Associated with polysomes, Binds strongly to poly(G), Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression, In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity), May play a role in the transport of mRNA from the nucleus to the cytoplasm, RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs, binds moderately to poly(U) but shows very little binding to poly(A) or poly(C), Translation repressor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FMR1, FMRP, FRAXA, Fragile X mental retardation protein 1, POF1, Protein FMR-1, POF
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFMRP (Ser500)
Short nameFMRP (Ser500) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFMRP (Ser500) (Antibody to)
Alternative techniqueantibodies
Identity 3775
Gene FMR1
Long gene name fragile X mental retardation 1
Synonyms gene POF1 POF
Synonyms gene name premature ovarian failure 1
Synonyms FMRP FRAXA MGC87458
Locus Xq27, 3
Discovery year 1992-01-17
GenBank acession X69962
Entrez gene record 2332
Pubmed identfication 1572655
RefSeq identity NM_002024
Havana BLAST/BLAT OTTHUMG00000022606
Locus Specific Databases Mental Retardation database LRG_762

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