Name : FMRP (Ser500) Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN9216600607
| Long name | ALEXA FLUOR 488 Conjugated, FMRP (Ser500) Polyclonal Antibody |
| Also known as | Anti-FMRP Ser500 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FMRP Ser500 |
| Specificity | This is a highly specific antibody against FMRP Ser500 |
| Modification | Phosphorylation |
| Modification Site | Ser500 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 480-530/632 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500 |
| Gene ID Number | 2332 |
| Swiss Prot | Q06787 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Associated with polysomes, Binds strongly to poly(G), Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression, In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity), May play a role in the transport of mRNA from the nucleus to the cytoplasm, RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs, binds moderately to poly(U) but shows very little binding to poly(A) or poly(C), Translation repressor |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | FMRP FRAXA MGC87458 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the FMRP (Ser500) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | FMRP (Ser500) |
| Short name | FMRP (Ser500) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, FMRP (Ser500) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3775 |
| Gene | FMR1 |
| Long gene name | fragile X mental retardation 1 |
| Synonyms gene | POF1 POF |
| Synonyms gene name | premature ovarian failure 1 |
| Locus | Xq27, 3 |
| Discovery year | 1992-01-17 |
| GenBank acession | X69962 |
| Entrez gene record | 2332 |
| Pubmed identfication | 1572655 |
| RefSeq identity | NM_002024 |
| Havana BLAST/BLAT | OTTHUMG00000022606 |
| Locus Specific Databases | Mental Retardation database LRG_762 |