Name : FMRP (Ser500) Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN1499193243
| Long name | ALEXA FLUOR 647 Conjugated, FMRP (Ser500) Polyclonal Antibody |
| Also known as | Anti-FMRP Ser500 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FMRP Ser500 |
| Specificity | This is a highly specific antibody against FMRP Ser500 |
| Modification | Phosphorylation |
| Modification Site | Ser500 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 480-530/632 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500 |
| Gene ID Number | 2332 |
| Swiss Prot | Q06787 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Associated with polysomes, Binds strongly to poly(G), Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression, In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity), May play a role in the transport of mRNA from the nucleus to the cytoplasm, RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs, binds moderately to poly(U) but shows very little binding to poly(A) or poly(C), Translation repressor |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | FMRP FRAXA MGC87458 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the FMRP (Ser500) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | FMRP (Ser500) |
| Short name | FMRP (Ser500) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, FMRP (Ser500) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 3775 |
| Gene | FMR1 |
| Long gene name | fragile X mental retardation 1 |
| Synonyms gene | POF1 POF |
| Synonyms gene name | premature ovarian failure 1 |
| Locus | Xq27, 3 |
| Discovery year | 1992-01-17 |
| GenBank acession | X69962 |
| Entrez gene record | 2332 |
| Pubmed identfication | 1572655 |
| RefSeq identity | NM_002024 |
| Havana BLAST/BLAT | OTTHUMG00000022606 |
| Locus Specific Databases | Mental Retardation database LRG_762 |