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FOXL2 (Ser263) Antibody

FOXL2 (Ser263) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFOXL2 (Ser263) Primary Polyclonal Antibody
Also known asFOXL2 (Ser263) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFOXL2 Ser263
SpecificityThis is a highly specific antibody against FOXL2 Ser263
Modification(s)Phosphorylation
Modification site(s)Ser263
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human FOXL2 around the phosphorylation site of Ser263
Gene ID number668
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activates SIRT1 transcription under cellular stress conditions, Activates transcription of OSR2, Critical factor essential for ovary differentiation and maintenance, Has apoptotic activity in ovarian cells, Is a regulator of CYP19 expression (By similarity), Is a transcriptional repressor of STAR, Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity), Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity), Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity), and repression of the genetic program for somatic testis determination, Transcriptional regulator
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BPES, BPES 1, BPES1, Blepharophimosis epicanthus inversus and ptosis, Blepharophimosis epicanthus inversus and ptosis 1, FOX L2, FOXL 2, FOXL2, FOXL2_HUMAN, Forkhead box protein L2, PFRK, PINTO, POF 3, POF3, blepharophimosis, epicanthus inversus and ptosis 1, forkhead box L2, forkhead transcription factor FOXL2, p-FOXL2 phospho S263, FOXL2 phospho S263
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFOXL2 (Ser263)
Short nameFOXL2 (Ser263) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameforkhead box L2 (Ser263) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BPES and BPES1 and PFRK and PINTO and POF3, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0019101 and female somatic sex determination and biological process this GO :0030154 and cell differentiation and biological process this GO :0030331 and estrogen receptor binding and molecular function this GO :0031624 and ubiquitin conjugating enzyme binding and molecular function this GO :0042703 and menstruation and biological process this GO :0043028 and cysteine-type endopeptidase regulator activity involved in apoptotic process and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048048 and embryonic eye morphogenesis and biological process this GO :0060014 and granulosa cell differentiation and biological process, FOXL2 and IDBG-58706 and ENSG00000183770 and 668, FOXL2 and IDBG-647332 and ENSBTAG00000031277 and 281770, Foxl2 and IDBG-192568 and ENSMUSG00000050397 and 26927, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0002074 and extraocular skeletal muscle development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006309 and apoptotic DNA fragmentation and biological process this GO :0006355 and regulation of transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0030331: estrogen receptor binding and also this GO :0031624: ubiquitin conjugating enzyme binding and also this GO :0043028: cysteine-type endopeptidase regulator activity involved in apoptotic process and also this GO :0043565: sequence-specific DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0030331: estrogen receptor binding, this GO :0031624: ubiquitin conjugating enzyme binding, this GO :0043028: cysteine-type endopeptidase regulator activity involved in apoptotic process, this GO :0043565: sequence-specific DNA binding, forkhead box L2
Identity 1092
Gene FOXL2
Long gene name forkhead box L2
Synonyms gene BPES
Synonyms BPES1
Locus 3q22, 3
Discovery year 1992-02-28
GenBank acession AF301906
Entrez gene record 668
Pubmed identfication 1941972
Classification Forkhead boxes
Havana BLAST/BLAT OTTHUMG00000159889
Locus Specific Databases Belgium , Ghent, LOVD - Center for Medical Genetics

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