Name : FOXL2 (Ser263) Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN3466348501
| Long name | ALEXA FLUOR 594 Conjugated, FOXL2 (Ser263) Polyclonal Antibody |
| Also known as | Anti-FOXL2 Ser263 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FOXL2 Ser263 |
| Specificity | This is a highly specific antibody against FOXL2 Ser263 |
| Modification | Phosphorylation |
| Modification Site | Ser263 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human FOXL2 around the phosphorylation site of Ser263 |
| Gene ID Number | 668 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activates SIRT1 transcription under cellular stress conditions, Activates transcription of OSR2, Critical factor essential for ovary differentiation and maintenance, Has apoptotic activity in ovarian cells, Is a regulator of CYP19 expression (By similarity), Is a transcriptional repressor of STAR, Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity), Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity), Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity), and repression of the genetic program for somatic testis determination, Transcriptional regulator |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | BPES1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | FOXL2 (Ser263) |
| Short name | FOXL2 (Ser263) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, forkhead box L2 (Ser263) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BPES and BPES1 and PFRK and PINTO and POF3, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0019101 and female somatic sex determination and biological process this GO :0030154 and cell differentiation and biological process this GO :0030331 and estrogen receptor binding and molecular function this GO :0031624 and ubiquitin conjugating enzyme binding and molecular function this GO :0042703 and menstruation and biological process this GO :0043028 and cysteine-type endopeptidase regulator activity involved in apoptotic process and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048048 and embryonic eye morphogenesis and biological process this GO :0060014 and granulosa cell differentiation and biological process, FOXL2 and IDBG-58706 and ENSG00000183770 and 668, FOXL2 and IDBG-647332 and ENSBTAG00000031277 and 281770, Foxl2 and IDBG-192568 and ENSMUSG00000050397 and 26927, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0002074 and extraocular skeletal muscle development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006309 and apoptotic DNA fragmentation and biological process this GO :0006355 and regulation of transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0030331: estrogen receptor binding and also this GO :0031624: ubiquitin conjugating enzyme binding and also this GO :0043028: cysteine-type endopeptidase regulator activity involved in apoptotic process and also this GO :0043565: sequence-specific DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0030331: estrogen receptor binding, this GO :0031624: ubiquitin conjugating enzyme binding, this GO :0043028: cysteine-type endopeptidase regulator activity involved in apoptotic process, this GO :0043565: sequence-specific DNA binding, forkhead box L2 |
| Identity | 1092 |
| Gene | FOXL2 |
| Long gene name | forkhead box L2 |
| Synonyms gene | BPES |
| Locus | 3q22, 3 |
| Discovery year | 1992-02-28 |
| GenBank acession | AF301906 |
| Entrez gene record | 668 |
| Pubmed identfication | 1941972 |
| Classification | Forkhead boxes |
| Havana BLAST/BLAT | OTTHUMG00000159889 |
| Locus Specific Databases | Belgium , Ghent, LOVD - Center for Medical Genetics |