Name : FOXL2 (Ser263) Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN2345779940
| Long name | ALEXA FLUOR 647 Conjugated, FOXL2 (Ser263) Polyclonal Antibody |
| Also known as | Anti-FOXL2 Ser263 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FOXL2 Ser263 |
| Specificity | This is a highly specific antibody against FOXL2 Ser263 |
| Modification | Phosphorylation |
| Modification Site | Ser263 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human FOXL2 around the phosphorylation site of Ser263 |
| Gene ID Number | 668 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activates SIRT1 transcription under cellular stress conditions, Activates transcription of OSR2, Critical factor essential for ovary differentiation and maintenance, Has apoptotic activity in ovarian cells, Is a regulator of CYP19 expression (By similarity), Is a transcriptional repressor of STAR, Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity), Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity), Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity), and repression of the genetic program for somatic testis determination, Transcriptional regulator |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | BPES1 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the FOXL2 (Ser263) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | FOXL2 (Ser263) |
| Short name | FOXL2 (Ser263) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, forkhead box L2 (Ser263) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | BPES and BPES1 and PFRK and PINTO and POF3, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0019101 and female somatic sex determination and biological process this GO :0030154 and cell differentiation and biological process this GO :0030331 and estrogen receptor binding and molecular function this GO :0031624 and ubiquitin conjugating enzyme binding and molecular function this GO :0042703 and menstruation and biological process this GO :0043028 and cysteine-type endopeptidase regulator activity involved in apoptotic process and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048048 and embryonic eye morphogenesis and biological process this GO :0060014 and granulosa cell differentiation and biological process, FOXL2 and IDBG-58706 and ENSG00000183770 and 668, FOXL2 and IDBG-647332 and ENSBTAG00000031277 and 281770, Foxl2 and IDBG-192568 and ENSMUSG00000050397 and 26927, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0002074 and extraocular skeletal muscle development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006309 and apoptotic DNA fragmentation and biological process this GO :0006355 and regulation of transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0030331: estrogen receptor binding and also this GO :0031624: ubiquitin conjugating enzyme binding and also this GO :0043028: cysteine-type endopeptidase regulator activity involved in apoptotic process and also this GO :0043565: sequence-specific DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0030331: estrogen receptor binding, this GO :0031624: ubiquitin conjugating enzyme binding, this GO :0043028: cysteine-type endopeptidase regulator activity involved in apoptotic process, this GO :0043565: sequence-specific DNA binding, forkhead box L2 |
| Identity | 1092 |
| Gene | FOXL2 |
| Long gene name | forkhead box L2 |
| Synonyms gene | BPES |
| Locus | 3q22, 3 |
| Discovery year | 1992-02-28 |
| GenBank acession | AF301906 |
| Entrez gene record | 668 |
| Pubmed identfication | 1941972 |
| Classification | Forkhead boxes |
| Havana BLAST/BLAT | OTTHUMG00000159889 |
| Locus Specific Databases | Belgium , Ghent, LOVD - Center for Medical Genetics |