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FOXL2 (Ser263) Antibody, Biotin Conjugated

FOXL2 (Ser263) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, FOXL2 (Ser263) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFOXL2 Ser263
SpecificityThis is a highly specific antibody against FOXL2 Ser263
ModificationPhosphorylation
Modification siteSer263
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human FOXL2 around the phosphorylation site of Ser263
Gene ID number668
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Activates SIRT1 transcription under cellular stress conditions, Activates transcription of OSR2, Critical factor essential for ovary differentiation and maintenance, Has apoptotic activity in ovarian cells, Is a regulator of CYP19 expression (By similarity), Is a transcriptional repressor of STAR, Participates in SMAD3-dependent transcription of FST via the intronic SMAD-binding element (By similarity), Prevents trans-differentiation of ovary to testis throught transcriptional repression of the Sertoli cell-promoting gene SOX9 (By similarity), Suppresses ESR1-mediated transcription of PTGS2/COX2 stimulated by tamoxifen (By similarity), and repression of the genetic program for somatic testis determination, Transcriptional regulator
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms BPES1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetFOXL2 (Ser263) Conjugated
Short name Conjugated, FOXL2 (Ser263) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, forkhead box L2 (Ser263) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BPES and BPES1 and PFRK and PINTO and POF3, DNA-templated and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0019101 and female somatic sex determination and biological process this GO :0030154 and cell differentiation and biological process this GO :0030331 and estrogen receptor binding and molecular function this GO :0031624 and ubiquitin conjugating enzyme binding and molecular function this GO :0042703 and menstruation and biological process this GO :0043028 and cysteine-type endopeptidase regulator activity involved in apoptotic process and molecular function this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043280 and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048048 and embryonic eye morphogenesis and biological process this GO :0060014 and granulosa cell differentiation and biological process, FOXL2 and IDBG-58706 and ENSG00000183770 and 668, FOXL2 and IDBG-647332 and ENSBTAG00000031277 and 281770, Foxl2 and IDBG-192568 and ENSMUSG00000050397 and 26927, nuclei, sequence-specific DNA binding, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001541 and ovarian follicle development and biological process this GO :0002074 and extraocular skeletal muscle development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006309 and apoptotic DNA fragmentation and biological process this GO :0006355 and regulation of transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0030331: estrogen receptor binding and also this GO :0031624: ubiquitin conjugating enzyme binding and also this GO :0043028: cysteine-type endopeptidase regulator activity involved in apoptotic process and also this GO :0043565: sequence-specific DNA binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0030331: estrogen receptor binding, this GO :0031624: ubiquitin conjugating enzyme binding, this GO :0043028: cysteine-type endopeptidase regulator activity involved in apoptotic process, this GO :0043565: sequence-specific DNA binding, forkhead box L2
Identity 1092
Gene FOXL2
Long gene name forkhead box L2
Synonyms gene BPES
Locus 3q22, 3
Discovery year 1992-02-28
GenBank acession AF301906
Entrez gene record 668
Pubmed identfication 1941972
Classification Forkhead boxes
Havana BLAST/BLAT OTTHUMG00000159889
Locus Specific Databases Belgium , Ghent, LOVD - Center for Medical Genetics

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