Name : FOXN1 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4078153913
| Long name | ALEXA FLUOR 488 Conjugated, FOXN1 Polyclonal Antibody |
| Also known as | Anti-FOXN1 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FOXN1 |
| Specificity | This is a highly specific antibody against FOXN1 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 350-400/648 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FOXN1 |
| Gene ID Number | 8456 |
| Swiss Prot | O15353 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | A mutation in this gene has been correlated with T-cell immunodeficiency, Alternative splicing in the 5' UTR of this gene has been observed, Jul 2008], This gene is orthologous to the mouse and rat genes and encodes a similar DNA-binding transcription factor that is thought to regulate keratin gene expression, [provided by RefSeq, and nail dystrophy, resulting in a severely compromised immune system, the skin disorder congenital alopecia, Mutations in the winged-helix transcription factor gene at the nude locus in mice and rats produce the pleiotropic phenotype of hairlessness and athymia |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | FKHL20 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the FOXN1 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | FOXN1 |
| Short name | FOXN1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, forkhead box N1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0006952 and defense response and biological process this GO :0008283 and cell proliferation and biological process this GO :0008544 and epidermis development and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0030216 and keratinocyte differentiation and biological process this GO :0033081 and regulation of T cell differentiation in thymus and biological process this GO :0035878 and nail development and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0048538 and thymus development and biological process this GO :0050673 and epithelial cell proliferation and biological process, FKHL20 and RONU and WHN, FOXN1 and IDBG-36752 and ENSG00000109101 and 8456, FOXN1 and IDBG-631668 and ENSBTAG00000013095 and 516724, Foxn1 and IDBG-202803 and ENSMUSG00000002057 and 15218, nuclei, sequence-specific DNA binding, this GO :0001942 and hair follicle development and biological process this GO :0002260 and lymphocyte homeostasis and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005634 and nucleus and cellular component this GO :0006355 and regulation of transcription, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0043565: sequence-specific DNA binding, this GO :0043565: sequence-specific DNA binding, forkhead box N1 |
| Identity | 12765 |
| Gene | FOXN1 |
| Long gene name | forkhead box N1 |
| Synonyms gene | WHN RONU |
| Synonyms gene name | winged-helix nude Rowett nude |
| Locus | 17q11, 2 |
| Discovery year | 1998-10-07 |
| GenBank acession | Y11739 |
| Entrez gene record | 8456 |
| Pubmed identfication | 9321431 |
| Classification | Forkhead boxes |
| Havana BLAST/BLAT | OTTHUMG00000132603 |
| Locus Specific Databases | FOXN1base: Mutation registry for T-cell immunodeficiency, and nail dystrophy (Previously known as WHNbase) LRG_61 , congenital alopecia |