Name : FoxO3a (Ser253) Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN7578113778
| Long name | FITC Conjugated, FoxO3a (Ser253) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | FoxO3a Ser253 |
| Specificity | This phosphorylation site is homologous to Ser252 in Mouse and Rat, This is a highly specific antibody against FoxO3a Ser253 |
| Modification | Phosphorylation |
| Modification site | Ser253 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 240-280/673 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | KLH conjugated synthetic phosphopeptide derived from human FoxO3a around the phosphorylation site of Ser253 |
| Gene ID number | 2309 |
| Swiss Prot | O43524 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation, Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3', including neuronal cell death upon oxidative stress, promotes induction of miR-34b and miR-34c expression, Transcriptional activator which triggers apoptosis in the absence of survival factors |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | AF6q21, AF6q21 protein, FKHRL1, FKHRL1P2, FOXO3, FOXO3A, Forkhead box protein O3, Forkhead in rhabdomyosarcoma-like 1, FOXO2 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | FoxO3a (Ser253) Conjugated |
| Short name | FITC Conjugated, FoxO3a (Ser253) Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, FoxO3a (Ser253) (Antibody to) |
| Alternative technique | antibodies |