Name : FOXP2 Antibody
Supplier : NJS POLY
Price :199
SKU : GEN2355652434
| Category | Antibody |
| Concentration | 09% sodium azide, 4 with 0, In 1X PBS pH 7 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | FOXP2 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus) , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, IF, WB |
| Recommended dilutions | Immunofluorescence: 1:10-1:50, Western blot: 1:1000 |
| Notes | Titration of the FOXP2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This FOXP2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | O15409 |
| Purity | Antigen affinity |
| Description | It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut, Multiple alternative transcripts encoding different isoforms have been identified in this gene, Mutations in this gene cause speech-language disorder 1 (SPCH1), The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, This gene is required for proper development of speech and language regions of the brain during embryogenesis, also known as autosomal dominant speech and language disorder with orofacial dyspraxia, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes, FOXP2 is a member of the forkhead/winged-helix (FOX) family of transcription factors |
| Immunogen | A portion of amino acids 657-684 from the human protein was used as the immunogen for this FOXP2 antibody |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the FOXP2 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | FOXP2 |
| Short name | FOXP2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | FOXP2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13875 |
| Gene | FOXP2 |
| Long gene name | forkhead box P2 |
| Synonyms gene | TNRC10 SPCH1 |
| Synonyms | CAGH44 |
| Synonyms name | trinucleotide repeat containing 10 forkhead/winged-helix transcription factor speech and language disorder 1 CAG repeat protein 44 |
| Locus | 7q31, 1 |
| Discovery year | 2000-11-20 |
| GenBank acession | U80741 |
| Entrez gene record | 93986 |
| Pubmed identfication | 11586359 9225980 |
| RefSeq identity | NM_014491 |
| Classification | Forkhead boxes Trinucleotide repeat containing |
| Havana BLAST/BLAT | OTTHUMG00000023131 |