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FOXP3 Antibody

FOXP3 Antibody size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration09% sodium azide, 4 with 0, In 1X PBS pH 7
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenFOXP3
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, WB
Recommended dilutionsWestern blot: 1:1000
NotesTitration of the anti-FOXP3 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis anti-FOXP3 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9BZS1
PurityAntigen affinity
Description Alternatively spliced transcript variants encoding different isoforms have been identified, Defects in this gene are the cause of immunodeficiency polyendocrinopathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome, enteropathy, Forkhead box P3 is a member of the forkhead/winged-helix family of transcriptional regulators
ImmunogenA portion of amino acids 397-423 from the human protein was used as the immunogen for this anti-FOXP3 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the anti-FOXP3 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetFOXP3
Short nameFOXP3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameforkhead box P3 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target CD25-positive, CD25-positive, DNA-templated and biological process this GO :0006357 and regulation of transcription from RNA polymerase II promoter and biological process this GO :0006366 and transcription from RNA polymerase II promoter and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009615 and response to virus and biological process this GO :0010628 and positive regulation of gene expression and biological process this GO :0031064 and negative regulation of histone deacetylation and biological process this GO :0032088 and negative regulation of NF-kappaB transcription factor activity and biological process this GO :0032689 and negative regulation of interferon-gamma production and biological process this GO :0032693 and negative regulation of interleukin-10 production and biological process this GO :0032703 and negative regulation of interleukin-2 production and biological process this GO :0032713 and negative regulation of interleukin-4 production and biological process this GO :0032714 and negative regulation of interleukin-5 production and biological process this GO :0032715 and negative regulation of interleukin-6 production and biological process this GO :0032720 and negative regulation of tumor necrosis factor production and biological process this GO :0032753 and positive regulation of interleukin-4 production and biological process this GO :0032792 and negative regulation of CREB transcription factor activity and biological process this GO :0032831 and positive regulation of CD4-positive, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046007 and negative regulation of activated T cell proliferation and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048294 and negative regulation of isotype switching to IgE isotypes and biological process this GO :0048302 and regulation of isotype switching to IgG isotypes and biological process this GO :0050672 and negative regulation of lymphocyte proliferation and biological process this GO :0050710 and negative regulation of cytokine secretion and biological process this GO :0050728 and negative regulation of inflammatory response and biological process this GO :0050777 and negative regulation of immune response and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051059 and NF-kappaB binding and molecular function this GO :0051525 and NFAT protein binding and molecular function, FOXP3 and IDBG-637186 and ENSBTAG00000013279 and 506053, FOXP3 and IDBG-66215 and ENSG00000049768 and 50943, Foxp3 and IDBG-128986 and ENSMUSG00000039521 and 20371, NFAT protein binding, alpha-beta regulatory T cell differentiation and biological process this GO :0002456 and T cell mediated immunity and biological process this GO :0002507 and tolerance induction and biological process this GO :0002513 and tolerance induction to self antigen and biological process this GO :0002637 and regulation of immunoglobulin production and biological process this GO :0002666 and positive regulation of T cell tolerance induction and biological process this GO :0002669 and positive regulation of T cell anergy and biological process this GO :0002677 and negative regulation of chronic inflammatory response and biological process this GO :0002725 and negative regulation of T cell cytokine production and biological process this GO :0002851 and positive regulation of peripheral T cell tolerance induction and biological process this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0003705 and RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and molecular function this GO :0003714 and transcription corepressor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0006338 and chromatin remodeling and biological process this GO :0006355 and regulation of transcription, alpha-beta regulatory T cell differentiation and biological process this GO :0032914 and positive regulation of transforming growth factor beta1 production and biological process this GO :0033092 and positive regulation of immature T cell proliferation in thymus and biological process this GO :0035035 and histone acetyltransferase binding and molecular function this GO :0035066 and positive regulation of histone acetylation and biological process this GO :0035067 and negative regulation of histone acetylation and biological process this GO :0042036 and negative regulation of cytokine biosynthetic process and biological process this GO :0042110 and T cell activation and biological process this GO :0042130 and negative regulation of T cell proliferation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042826 and histone deacetylase binding and molecular function this GO :0043029 and T cell homeostasis and biological process this GO :0043234 and protein complex and cellular component this GO :0043433 and negative regulation of sequence-specific DNA binding transcription factor activity and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0045066 and regulatory T cell differentiation and biological process this GO :0045077 and negative regulation of interferon-gamma biosynthetic process and biological process this GO :0045085 and negative regulation of interleukin-2 biosynthetic process and biological process this GO :0045591 and positive regulation of regulatory T cell differentiation and biological process this GO :0045892 and negative regulation of transcription, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001782 and B cell homeostasis and biological process this GO :0001816 and cytokine production and biological process this GO :0002262 and myeloid cell homeostasis and biological process this GO :0002361 and CD4-positive, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity and also this GO :0003714: transcription corepressor activity and also this GO :0005515: protein binding and also this GO :0035035: histone acetyltransferase binding and also this GO :0042803: protein homodimerization activity and also this GO :0042826: histone deacetylase binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0046872: metal ion binding and also this GO :0051059: NF-kappaB binding and also this GO :0051525: NFAT protein binding, this GO :0003705: RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity, this GO :0003714: transcription corepressor activity, this GO :0005515: protein binding, this GO :0035035: histone acetyltransferase binding, this GO :0042803: protein homodimerization activity, this GO :0042826: histone deacetylase binding, this GO :0043565: sequence-specific DNA binding, this GO :0046872: metal ion binding, this GO :0051059: NF-kappaB binding, this GO :0051525: NFAT protein binding, forkhead box P3
Identity 6106
Gene FOXP3
Long gene name forkhead box P3
Synonyms gene IPEX
Synonyms gene name X-linked , enteropathy, immune dysregulation, polyendocrinopathy
Synonyms JM2 XPID AIID PIDX DIETER SCURFIN
Locus Xp11, 23
Discovery year 2000-05-05
Entrez gene record 50943
Pubmed identfication 10677306 11138001
RefSeq identity NM_014009
Classification Forkhead boxes
Havana BLAST/BLAT OTTHUMG00000024135
Locus Specific Databases FOXP3base: Mutation registry for Immunodysregulation, IPEX Mental Retardation database LRG_62 , X-linked, and enteropathy, polyendocrinopathy

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