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Frizzled 7 Antibody

Frizzled 7 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFrizzled 7 Primary Polyclonal Antibody
Also known asFrizzled 7 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFrizzled 7
SpecificityThis is a highly specific antibody against Frizzled 7
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range550-574/574
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Frizzled 7
Gene ID number8324
Swiss ProtO75084
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes, which leads to the activation of disheveled proteins, Receptor for Wnt proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FZD7, Frizzled-7, Fz-7, hFz7, FzE3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFrizzled 7
Short nameFrizzled 7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFrizzled 7 (Antibody to)
Alternative techniqueantibodies
Identity 4045
Gene FZD7
Long gene name frizzled class receptor 7
Synonyms gene name frizzled (Drosophila) homolog 7 frizzled homolog 7 (Drosophila) frizzled 7, seven transmembrane spanning receptor frizzled family receptor 7
Synonyms FzE3
Locus 2q33, 1
Discovery year 1998-09-17
GenBank acession AB010881
Entrez gene record 8324
Pubmed identfication 9707618 9813155
RefSeq identity NM_003507
Classification Class F frizzled , G protein-coupled receptors
Havana BLAST/BLAT OTTHUMG00000132841

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