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Frizzled 7 Antibody, ALEXA FLUOR 488

Frizzled 7 Antibody, ALEXA FLUOR 488 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, Frizzled 7 Polyclonal Antibody
Also known asAnti-Frizzled 7 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenFrizzled 7
SpecificityThis is a highly specific antibody against Frizzled 7
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen range550-574/574
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Frizzled 7
Gene ID Number8324
Swiss ProtO75084
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, Both pathways seem to involve interactions with G-proteins, May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues, Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes, which leads to the activation of disheveled proteins, Receptor for Wnt proteins
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms FzE3
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Frizzled 7 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetFrizzled 7
Short nameFrizzled 7 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, Frizzled 7 (Antibody to)
Alternative techniqueantibodies
Identity 4045
Gene FZD7
Long gene name frizzled class receptor 7
Synonyms gene name frizzled (Drosophila) homolog 7 frizzled homolog 7 (Drosophila) frizzled 7, seven transmembrane spanning receptor frizzled family receptor 7
Locus 2q33, 1
Discovery year 1998-09-17
GenBank acession AB010881
Entrez gene record 8324
Pubmed identfication 9707618 9813155
RefSeq identity NM_003507
Classification Class F frizzled , G protein-coupled receptors
Havana BLAST/BLAT OTTHUMG00000132841

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